The Link Between Weight-Loss Medication (i.e. Ozempic) and Hair by Sidona Berhe
Weight loss medications like Ozempic and Wegovy are becoming hope for individuals managing obesity and striving toward long-term health goals. While the physical transformation brought by these drugs is worth celebrating, it is reasonable to wonder if these medications have any effect on our hair health. In order to explore the connection between weight-loss medication and hair, it is crucial to understand what those medications are, how they work, and what effect they have on the body.
Weight-loss medications are pharmacologic agents that are designed to help individuals lose weight by targeting specific biological mechanisms that regulate appetite, metabolism, and fat absorption. Among the most widely known medications are GLP-1 receptor agonists, such as Ozempic (semaglutide), Wegovy (a higher-dose version of semaglutide), and Manjaro. These medications mimic natural hormones that control appetite and glucose metabolism by reducing appetite, slowing gastric emptying by allowing food to stay in the stomach longer, and improving insulin sensitivity which is particularly beneficial for diabetic patients. As a result of these medications, weight loss outcomes vary, but on average, patients can expect a reduction of 15-20% of their body weight. However, maintaining this weight loss typically requires long-term use, since stopping the medication often leads to weight regain. This then brings up an important question, can such powerful, long term shifts in your body have an impact on your hair health?
While studies have shown there may not be a direct relationship between hair and weight-loss medications, clinical trials published by the National Institutes of Health (NIH) showed that approximately 3% of participants taking 2.4mg of semaglutide (Ozempic) reported hair loss. Additionally, another study found that fewer than 1% of people experienced non-scarring hair loss (telogen effluvium) within six months of starting weight-loss medications, suggesting that while the risk is low, it is still possible. Additionally, Amphetamine- which is also prescribed as a weight-loss medication, has been linked to more severe forms of alopecia areata in some patients, particularly when used over several months as indicated by a study published by the NIH in 2019. But why does this happen? The answer lies in how these medications are affecting the body and the impact it has for hair growth. Rapid weight loss whether through surgery, extreme dieting, or medication can shock the hair growth cycle triggering a condition where hair prematurely enters the shedding phase. Additionally, these medications can also contribute to nutrient deficiencies in the body, as essential vitamins and minerals needed to support healthy hair growth may not be adequately absorbed or replenished. While the medication itself may not directly damage hair follicles, the combination of rapid weight loss and lack of proper nutrition can lead to increased hair shedding, thinning and breakage.
So what can be done? Understanding the link between hair and weight-loss medication will allow individuals to have a better weight-loss journey experience and explore if there are any needs for alternative and hair-friendly ways for losing weight. In this case, diets like the mediterranean diet which are rich in fruits, vegetables, lean proteins, and healthy fats can support both metabolic health and hair health. Additionally, incorporating exercise and a healthy dietary plan can also support weight loss while reducing cortisol-related hair fall out. Whether you are exploring weight-loss medication or considering alternative routines, it's important to remember: supporting your weight-loss journey means supporting your hair health- from the inside out.
References:
Chavez-Alvarez, S., Villarreal-Alfaro-Lopez, A., Vazquez-Martinez, O., & Villarreal-Martinez, A. (2019). Diffuse alopecia areata associated with weight-loss pills. International Journal of Trichology, 11(6), 236. https://doi.org/10.4103/ijt.ijt_101_19
Columbia Surgery. (2024). The Ozempic Effect: Everything You Need to Know About Medical Weight Loss | Columbia Surgery. Columbia Surgery.org. https://columbiasurgery.org/news/ozempic-effect-everything-you-need-know-about-medical-weight-loss
Kim, J. Y. (2020). Optimal diet strategies for weight loss and weight loss maintenance. Journal of Obesity & Metabolic Syndrome, 30(1), 20–31. https://doi.org/10.7570/jomes2006
Nett, K. (2022, May 26). Radiant hair, skin, nails naturally. Mayo Clinic Health System. https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/get-radiant-hair-skin-and-nails-naturally